Chemicals and Drugs

Norgestrel

A synthetic progestational agent with actions similar to those of PROGESTERONE. This racemic or (+-)-form has about half the potency of the levo form (LEVONORGESTREL). Norgestrel is used as a contraceptive, ovulation inhibitor, and for the control of menstrual disorders and endometriosis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic progestational agent with actions similar to those of PROGESTERONE. This racemic or (+-)-form has about half the potency of the levo form (LEVONORGESTREL). Norgestrel is used as a contraceptive, ovulation inhibitor, and for the control of menstrual disorders and endometriosis.

Chemical Identity

Chemical Information

Molecular Formula
C21H28O2
Molecular Weight
312.4 g/mol
IUPAC Name
(8R,9S,10R,13S,14S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKey
WWYNJERNGUHSAO-CULCCENASA-N
SMILES
CC[C@]12CC[C@H]3[C@H]([C@@H]1CCC2(C#C)O)CCC4=CC(=O)CC[C@H]34
MeSH Unique ID
D009644
Source
PubChem CID 16051930

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)-(+-)-
  • DL-Norgestrel
  • DL Norgestrel
  • Neogest
  • Ovrette
  • Postinor
  • Wy-3707
  • Wy 3707
  • Wy3707

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

72

MeSH Record

Previous Indexing

  • Contraceptives, Oral (1966-1971)
  • Ketones (1966-1971)
  • Pregnanes (1968-1971)
  • Progestational Hormones (1966-1971)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.668w.651.693.762w

AMA Style

References

  1. National Library of Medicine. Norgestrel. Medical Subject Headings (MeSH). 2026. Unique ID D009644. http://id.nlm.nih.gov/mesh/2026/D009644
  2. Norgestrel. In: Wikipedia. https://en.wikipedia.org/wiki/Norgestrel
  3. Norgestrel. In: Wikidata. https://www.wikidata.org/wiki/Q7051185
  4. Norgestrel. In: PubChem Compound. CID 16051930. https://pubchem.ncbi.nlm.nih.gov/compound/16051930