Chemicals and Drugs

Norepinephrine Plasma Membrane Transport Proteins

Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of noradrenergic neurons. They remove NOREPINEPHRINE from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. The norepinephrine transporter regulates signal amplitude and duration at noradrenergic synapses and is the target of ADRENERGIC UPTAKE INHIBITORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of noradrenergic neurons. They remove NOREPINEPHRINE from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. The norepinephrine transporter regulates signal amplitude and duration at noradrenergic synapses and is the target of ADRENERGIC UPTAKE INHIBITORS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

20 entry terms
  • NET Protein, Neuronal
  • Neurotransmitter Transporters, Noradrenaline-Specific
  • Noradrenaline Plasma Membrane Transport Proteins
  • Noradrenaline Transporter
  • Norepinephrine Plasma Membrane Transporter Proteins
  • Norepinephrine Plasma Membrane Transporters
  • Norepinephrine Transporter
  • Norepinephrine Transporter Protein
  • SLC6A2 Protein
  • Sodium-Dependent Noradrenaline Transporter
  • Solute Carrier Family 6 Member 2
  • Neuronal NET Protein
  • Neurotransmitter Transporters, Noradrenaline Specific
  • Noradrenaline Transporter, Sodium-Dependent
  • Noradrenaline-Specific Neurotransmitter Transporters
  • Sodium Dependent Noradrenaline Transporter
  • Transporter Protein, Norepinephrine
  • Transporter, Noradrenaline
  • Transporter, Norepinephrine
  • Transporters, Noradrenaline-Specific Neurotransmitter

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1991)

MeSH Record

Previous Indexing

  • Carrier Proteins (1991-2004)
  • Symporters (2005)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.450w.625w.186
  2. D12.776w.157w.530w.562w.374.500.750
  3. D12.776w.157w.530w.937w.600
  4. D12.776w.543w.585w.450w.625w.186
  5. D12.776w.543w.585w.562w.374.500.750
  6. D12.776w.543w.585w.937w.700

AMA Style

References

  1. National Library of Medicine. Norepinephrine Plasma Membrane Transport Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D050484. http://id.nlm.nih.gov/mesh/2026/D050484
  2. Norepinephrine Plasma Membrane Transport Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q7050954