Structured Summary
Abstract
A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Chemical Identity
Chemical Information
- Molecular Formula
- C12H21N5O2S2
- Molecular Weight
- 331.5 g/mol
- CAS Registry No.
- 76963-41-2
- IUPAC Name
- 1-N'-[2-[[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
- InChIKey
- SGXXNSQHWDMGGP-UHFFFAOYSA-N
- SMILES
- CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C
- MeSH Unique ID
- D016567
- Source
- PubChem CID 4513
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- N-(2-(((2-((Dimethylamino)methyl)-4-thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine
- Axid
- LY-139037
- LY 139037
- LY139037
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
92; was NIZATIDINE (NM) 1985-91
MeSH Record
Previous Indexing
- Thiazoles (1966-1991)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Nizatidine. Medical Subject Headings (MeSH). 2026. Unique ID D016567. http://id.nlm.nih.gov/mesh/2026/D016567
- Nizatidine. In: Wikipedia. https://en.wikipedia.org/wiki/Nizatidine
- Nizatidine. In: Wikidata. https://www.wikidata.org/wiki/Q1188290
- Nizatidine. In: PubChem Compound. CID 4513. https://pubchem.ncbi.nlm.nih.gov/compound/4513