Chemicals and Drugs

Nitromifene

A non-steroidal estrogen antagonist (as the 1:1 citrate) most commonly used as a research tool in animal studies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-steroidal estrogen antagonist (as the 1:1 citrate) most commonly used as a research tool in animal studies.

Chemical Identity

Chemical Information

Molecular Formula
C27H28N2O4
Molecular Weight
444.5 g/mol
CAS Registry No.
10448-84-7
IUPAC Name
1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]pyrrolidine
InChIKey
MFKMXUFMHOCZHP-UHFFFAOYSA-N
SMILES
COC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)[N+](=O)[O-])C3=CC=C(C=C3)OCCN4CCCC4
MeSH Unique ID
D009594
Source
PubChem CID 22150

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Nitromiphene
  • CI-628
  • CI628
  • CN-55,945-27
  • CN-55945-27
  • Nitromifene Citrate
  • Nitromifene Citrate (1:1)
  • Nitromifene, (E)-Isomer
  • Nitromifene, (Z)-Isomer
  • CI 628

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under PYRROLIDINES 1979-90; was CI 628 see under PYRROLIDINES 1975-78

MeSH Record

Previous Indexing

  • Anisoles (1972-1974)
  • Pyrrolidines (1972-1974)
  • Styrenes (1972-1974)

MeSH Hierarchy

Tree Number

  1. D03w.383.773.610w

AMA Style

References

  1. National Library of Medicine. Nitromifene. Medical Subject Headings (MeSH). 2026. Unique ID D009594. http://id.nlm.nih.gov/mesh/2026/D009594
  2. Nitromifene. In: Wikipedia. https://en.wikipedia.org/wiki/Nitromifene
  3. Nitromifene. In: Wikidata. https://www.wikidata.org/wiki/Q27262013
  4. Nitromifene. In: PubChem Compound. CID 22150. https://pubchem.ncbi.nlm.nih.gov/compound/22150