Chemicals and Drugs

Nitrofurazone

A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS.

Chemical Identity

Chemical Information

Molecular Formula
C6H6N4O4
Molecular Weight
198.14 g/mol
IUPAC Name
[(5-nitrofuran-2-yl)methylideneamino]urea
InChIKey
IAIWVQXQOWNYOU-UHFFFAOYSA-N
SMILES
C1=C(OC(=C1)[N+](=O)[O-])C=NNC(=O)N
MeSH Unique ID
D009583
Source
PubChem CID 1839

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Nitrofural
  • Furacilin
  • Furacillin
  • Furacin
  • Nitrofurazone, Calcium (2:1) Salt

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Nitrofurazone. Medical Subject Headings (MeSH). 2026. Unique ID D009583. http://id.nlm.nih.gov/mesh/2026/D009583
  2. Nitrofurazone. In: Wikipedia. https://en.wikipedia.org/wiki/Nitrofurazone
  3. Nitrofurazone. In: Wikidata. https://www.wikidata.org/wiki/Q425502
  4. Nitrofurazone. In: PubChem Compound. CID 1839. https://pubchem.ncbi.nlm.nih.gov/compound/1839