Chemicals and Drugs

Nitrite Reductase (NAD(P)H)

An enzyme found primarily in BACTERIA and FUNGI that catalyzes the oxidation of ammonium hydroxide to nitrite. It is an iron-sulfur HEME; FLAVOPROTEIN containing siroheme and can utilize both NAD and NADP as cofactors. This enzyme was formerly classified as EC 1.6.6.4.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme found primarily in BACTERIA and FUNGI that catalyzes the oxidation of ammonium hydroxide to nitrite. It is an iron-sulfur HEME; FLAVOPROTEIN containing siroheme and can utilize both NAD and NADP as cofactors. This enzyme was formerly classified as EC 1.6.6.4.

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Classification

Broader headings

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MeSH Record

Synonyms

11 entry terms
  • Assimilatory Nitrite Reductase
  • NAD(P)H-Nitrite Reductase
  • NADH-Dependent Nitrite Reductase
  • NADH-Nitrite Oxidoreductase
  • NADPH-Nitrite Reductase
  • Nitrite Reductase (NAD(P)H(2))
  • Nitrite Reductase (Reduced Nicotinamide Adenine Dinucleotide (Phosphate))
  • NADH Dependent Nitrite Reductase
  • NADH Nitrite Oxidoreductase
  • NADPH Nitrite Reductase
  • Nitrite Reductase, NADH-Dependent

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with NITRATE REDUCTASE (NAD(P)H)

MeSH Record

History Note

2006(1981)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Nitrite Reductase (NAD(P)H). Medical Subject Headings (MeSH). 2026. Unique ID D050898. http://id.nlm.nih.gov/mesh/2026/D050898
  2. Nitrite Reductase (NAD(P)H). In: Wikipedia. https://en.wikipedia.org/wiki/Nitrite_reductase_(NAD(P)H)
  3. Nitrite Reductase (NAD(P)H). In: Wikidata. https://www.wikidata.org/wiki/Q3574938