Chemicals and Drugs

Nitrendipine

A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.

Chemical Identity

Chemical Information

Molecular Formula
C18H20N2O6
Molecular Weight
360.4 g/mol
CAS Registry No.
39562-70-4
IUPAC Name
5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey
PVHUJELLJLJGLN-UHFFFAOYSA-N
SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C
MeSH Unique ID
D009568
Source
PubChem CID 4507

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

45 entry terms
  • Balminil
  • Bay e 5009
  • Bayotensin
  • Baypresol
  • Baypress
  • Gericin
  • Jutapress
  • Nidrel
  • Niprina
  • Nitre AbZ
  • Nitre-Puren
  • Nitregamma
  • Nitren 1A Pharma
  • Nitren Lich
  • Nitren acis
  • Nitrend KSK
  • Nitrendepat
  • Nitrendi Biochemie
  • Nitrendidoc
  • Nitrendimerck
  • Nitrendipin AL
  • Nitrendipin Apogepha
  • Nitrendipin Atid
  • Nitrendipin Basics
  • Nitrendipin Heumann
  • Nitrendipin Jenapharm
  • Nitrendipin Lindo
  • Nitrendipin Stada
  • Nitrendipin beta
  • Nitrendipin-ratiopharm
  • Nitrendipino Bayvit
  • Nitrendipino Ratiopharm
  • Nitrensal
  • Nitrepress
  • Tensogradal
  • Trendinol
  • Vastensium
  • nitrendipin von ct
  • nitrendipin-corax
  • Nitre Puren
  • NitrePuren
  • Nitrendipin ratiopharm
  • Nitrendipinratiopharm
  • nitrendipin corax
  • nitrendipincorax

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Nifedipine/analogs & derivatives (1982-1986)
  • Pyridines (1966-1981)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Nitrendipine. Medical Subject Headings (MeSH). 2026. Unique ID D009568. http://id.nlm.nih.gov/mesh/2026/D009568
  2. Nitrendipine. In: Wikipedia. https://en.wikipedia.org/wiki/Nitrendipine
  3. Nitrendipine. In: Wikidata. https://www.wikidata.org/wiki/Q416584
  4. Nitrendipine. In: PubChem Compound. CID 4507. https://pubchem.ncbi.nlm.nih.gov/compound/4507