Structured Summary
Abstract
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
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Classification
Broader headings
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Synonyms
8 entry terms
- NAMPT Protein
- NAmPRTase
- NMN Pyrophosphorylase
- Pre-B-Cell Colony-Enhancing Factor
- Visfatin
- Colony-Enhancing Factor, Pre-B-Cell
- Phosphoribosyltransferase, Nicotinamide
- Pre B Cell Colony Enhancing Factor
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2008 (1982)
MeSH Record
Previous Indexing
- Pentosyltransferases (1972-2007)
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AMA Style
References
- National Library of Medicine. Nicotinamide Phosphoribosyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D054409. http://id.nlm.nih.gov/mesh/2026/D054409
- Nicotinamide Phosphoribosyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q24776198