Chemicals and Drugs

Neuromuscular Depolarizing Agents

Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation.

MeSH Record

Classification

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • Depolarizing Blockers
  • Depolarizing Muscle Relaxants
  • Muscle Relaxants, Depolarizing
  • Agents, Neuromuscular Depolarizing
  • Blockers, Depolarizing
  • Depolarizing Agents, Neuromuscular
  • Relaxants, Depolarizing Muscle

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

70; LEPTOCURARES was see NEUROMUSCULAR DEPOLARIZING AGENTS 1970-92; MUSCLE RELAXANTS was see under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74, was heading 1963-69

MeSH Record

Previous Indexing

  • Muscles (1966-1969)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 140

AMA Style

References

  1. National Library of Medicine. Neuromuscular Depolarizing Agents. Medical Subject Headings (MeSH). 2026. Unique ID D009467. http://id.nlm.nih.gov/mesh/2026/D009467
  2. Neuromuscular Depolarizing Agents. In: Wikidata. https://www.wikidata.org/wiki/Q50430102