Chemicals and Drugs

Neurofibromin 2

A membrane protein homologous to the ERM (Ezrin-Radixin-Moesin) family of cytoskeleton-associated proteins which regulate physical properties of membranes. Alterations in neurofibromin 2 are the cause of NEUROFIBROMATOSIS 2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A membrane protein homologous to the ERM (Ezrin-Radixin-Moesin) family of cytoskeleton-associated proteins which regulate physical properties of membranes. Alterations in neurofibromin 2 are the cause of NEUROFIBROMATOSIS 2.

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Classification

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MeSH Record

Synonyms

10 entry terms
  • Merlin
  • Moesin-Ezrin-Radixin-Like Protein
  • NF2 Gene Product
  • Neurofibromatosis 2 Gene Product
  • Neurofibromatosis Type 2 Protein
  • Schwannomin
  • Schwannomin Protein
  • Gene Product, NF2
  • Moesin Ezrin Radixin Like Protein
  • Protein, Schwannomin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002; for SCHWANNOMIN PROTEIN use NEUROFIBROMIN 2 (NM) 1993-2001

MeSH Record

Previous Indexing

  • Membrane Proteins (1993-2001)
  • Neoplasm Proteins (1993-2001)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Neurofibromin 2. Medical Subject Headings (MeSH). 2026. Unique ID D025581. http://id.nlm.nih.gov/mesh/2026/D025581
  2. Neurofibromin 2. In: Wikipedia. https://en.wikipedia.org/wiki/Merlin_(protein)
  3. Neurofibromin 2. In: Wikidata. https://www.wikidata.org/wiki/Q410233