Structured Summary
Abstract
A protein found most abundantly in the nervous system. Defects or deficiencies in this protein are associated with NEUROFIBROMATOSIS 1, Watson syndrome, and LEOPARD syndrome. Mutations in the gene (GENE, NEUROFIBROMATOSIS 1) affect two known functions: regulation of ras-GTPase and tumor suppression.
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Broader headings
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Synonyms
9 entry terms
- NF-1 Protein
- NF1 GRP
- NF1 Protein
- NF1-GAP-Related Protein
- Neurofibromatosis Type 1 Gene Product
- Neurofibromatosis Type 1 Protein
- Neurofibromin
- NF 1 Protein
- NF1 GAP Related Protein
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2002
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Previous Indexing
- Nerve Tissue Proteins (1995-2001)
- Proteins (1990-1999)
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AMA Style
References
- National Library of Medicine. Neurofibromin 1. Medical Subject Headings (MeSH). 2026. Unique ID D025542. http://id.nlm.nih.gov/mesh/2026/D025542
- Neurofibromin 1. In: Wikipedia. https://en.wikipedia.org/wiki/Neurofibromin
- Neurofibromin 1. In: Wikidata. https://www.wikidata.org/wiki/Q411610