Structured Summary
Abstract
A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (ERB-B2 RECEPTOR TYROSINE KINASES). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.
MeSH Record
Classification
Broader headings
Related Concepts
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Synonyms
8 entry terms
- NDF Protein
- NRG1 Protein
- Neuregulin 1
- GGF Protein
- Glial Growth Factor
- Heregulin
- neu Differentiation Factor
- Differentiation Factor, neu
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not confuse entry term GLIAL GROWTH FACTOR with GLIA MATURATION FACTOR
MeSH Record
History Note
2000; use NEUREGULIN-1 (NM) 1993-1999; for GLIAL GROWTH FACTOR use GLIA MATURATION FACTOR (NM) 1980-1999
MeSH Record
Previous Indexing
- Glycoproteins (1986-1999)
- Nerve Tissue Proteins (1980-1999)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Neuregulin-1. Medical Subject Headings (MeSH). 2026. Unique ID D020890. http://id.nlm.nih.gov/mesh/2026/D020890
- Neuregulin-1. In: Wikidata. https://www.wikidata.org/wiki/Q24782549