Chemicals and Drugs

Neopterin

A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of BIOPTERINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of BIOPTERINS.

Chemical Identity

Chemical Information

Molecular Formula
C9H11N5O4
Molecular Weight
253.22 g/mol
CAS Registry No.
2009-64-5
IUPAC Name
2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-3H-pteridin-4-one
InChIKey
BMQYVXCPAOLZOK-XINAWCOVSA-N
SMILES
C1=C(N=C2C(=O)NC(=NC2=N1)N)[C@@H]([C@@H](CO)O)O
MeSH Unique ID
D019798
Source
PubChem CID 135398721

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

8 entry terms
  • 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone
  • Monapterin
  • Neopterin, (R*, R*)-Isomer
  • Neopterin, (erythro-D)-Isomer
  • Neopterin, (erythro-L)-Isomer
  • Neopterin, (threo-D)-Isomer
  • Neopterin, (threo-L)-Isomer
  • Umanopterin

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

98; use NEOPTERIN (NM) 1979-97

MeSH Record

Previous Indexing

  • Biopterin/analogs & derivatives (1977-1997)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.733.631.202w.500w
  2. D08.211w.090w.500w

AMA Style

References

  1. National Library of Medicine. Neopterin. Medical Subject Headings (MeSH). 2026. Unique ID D019798. http://id.nlm.nih.gov/mesh/2026/D019798
  2. Neopterin. In: Wikipedia. https://en.wikipedia.org/wiki/Neopterin
  3. Neopterin. In: Wikidata. https://www.wikidata.org/wiki/Q908292
  4. Neopterin. In: PubChem Compound. CID 135398721. https://pubchem.ncbi.nlm.nih.gov/compound/135398721