Diseases

Nelson Syndrome

A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1991(1978)

MeSH Record

Previous Indexing

  • Adenoma (1966-1977)
  • Pigmentation Disorders (1966-1977)
  • Pituitary Neoplasms (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. C04w.588.322w.609.145.500w
  2. C10w.228w.140w.617w.738w.675.149.500w
  3. C19w.344w.609.145.500w
  4. C19w.700w.734.145.500w

AMA Style

References

  1. National Library of Medicine. Nelson Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D009347. http://id.nlm.nih.gov/mesh/2026/D009347
  2. Nelson Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Nelson%27s_syndrome
  3. Nelson Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q2165266