Chemicals and Drugs

Nelfinavir

A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.

Chemical Identity

Chemical Information

Molecular Formula
C32H45N3O4S
Molecular Weight
567.8 g/mol
CAS Registry No.
159989-64-7
IUPAC Name
(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide
InChIKey
QAGYKUNXZHXKMR-HKWSIXNMSA-N
SMILES
CC1=C(C=CC=C1O)C(=O)N[C@@H](CSC2=CC=CC=C2)[C@@H](CN3C[C@H]4CCCC[C@H]4C[C@H]3C(=O)NC(C)(C)C)O
MeSH Unique ID
D019888
Source
PubChem CID 64143

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • AG 1343
  • AG-1343
  • AG1343
  • Nelfinavir Mesylate
  • Nelfinavir Monomethane Sulfonate
  • Viracept
  • Mesylate, Nelfinavir
  • Monomethane Sulfonate, Nelfinavir
  • Sulfonate, Nelfinavir Monomethane

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

98; use NELFINAVIR (NM) 1995-97

MeSH Record

Previous Indexing

  • Isoquinolines (1995-1997)
  • Sulfonic Acids (1995-1997)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.531.520w

AMA Style

References

  1. National Library of Medicine. Nelfinavir. Medical Subject Headings (MeSH). 2026. Unique ID D019888. http://id.nlm.nih.gov/mesh/2026/D019888
  2. Nelfinavir. In: Wikipedia. https://en.wikipedia.org/wiki/Nelfinavir
  3. Nelfinavir. In: Wikidata. https://www.wikidata.org/wiki/Q423366
  4. Nelfinavir. In: PubChem Compound. CID 64143. https://pubchem.ncbi.nlm.nih.gov/compound/64143