Chemicals and Drugs

Nebivolol

A cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients.

Chemical Identity

Chemical Information

Molecular Formula
C22H25F2NO4
Molecular Weight
405.4 g/mol
CAS Registry No.
118457-14-0
IUPAC Name
1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol
InChIKey
KOHIRBRYDXPAMZ-UHFFFAOYSA-N
SMILES
C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
MeSH Unique ID
D000068577
Source
PubChem CID 71301

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Alpha,Alpha'-(Iminobis(Methylene))bis(6-Fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol
  • Bystolic
  • Lobivon
  • Nebilet
  • Nebivolol Hydrochloride
  • R 67555
  • R-67555
  • Silostar
  • 67555, R
  • Hydrochloride, Nebivolol
  • R67555

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1987)

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.291.491w
  2. D02w.092w.063w.291.503w
  3. D03w.383.663.283.755w
  4. D03w.633.100.150.755w

AMA Style

References

  1. National Library of Medicine. Nebivolol. Medical Subject Headings (MeSH). 2026. Unique ID D000068577. http://id.nlm.nih.gov/mesh/2026/D000068577
  2. Nebivolol. In: Wikipedia. https://en.wikipedia.org/wiki/Nebivolol
  3. Nebivolol. In: Wikidata. https://www.wikidata.org/wiki/Q418130
  4. Nebivolol. In: PubChem Compound. CID 71301. https://pubchem.ncbi.nlm.nih.gov/compound/71301