Chemicals and Drugs

Natamycin

Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically.

Chemical Identity

Chemical Information

Molecular Formula
C33H47NO13
Molecular Weight
665.7 g/mol
CAS Registry No.
7681-93-8
IUPAC Name
(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
InChIKey
NCXMLFZGDNKEPB-FFPOYIOWSA-N
SMILES
C[C@@H]1C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@@H]3[C@H](O3)/C=C/C(=O)O1)O)O)O)C(=O)O)O[C@H]4[C@H]([C@H]([C@@H]([C@H](O4)C)O)N)O
MeSH Unique ID
D010866
Source
PubChem CID 5284447

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Pimaricin
  • Tennecetin
  • Myprozine
  • Pimafucin

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not use /biosyn unless by living matter

MeSH Record

History Note

90(66); was PIMARICIN 1966-89

MeSH Hierarchy

Tree Number

  1. D02w.540w.505w.550w

AMA Style

References

  1. National Library of Medicine. Natamycin. Medical Subject Headings (MeSH). 2026. Unique ID D010866. http://id.nlm.nih.gov/mesh/2026/D010866
  2. Natamycin. In: Wikipedia. https://en.wikipedia.org/wiki/Natamycin
  3. Natamycin. In: Wikidata. https://www.wikidata.org/wiki/Q248466
  4. Natamycin. In: PubChem Compound. CID 5284447. https://pubchem.ncbi.nlm.nih.gov/compound/5284447