Structured Summary
Abstract
A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
Chemical Identity
Chemical Information
- Molecular Formula
- C19H21NO3
- Molecular Weight
- 311.4 g/mol
- CAS Registry No.
- 62-67-9
- IUPAC Name
- (4R,4aR,7S,7aR,12bS)-3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
- InChIKey
- UIQMVEYFGZJHCZ-SSTWWWIQSA-N
- SMILES
- C=CCN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
- MeSH Unique ID
- D009269
- Source
- PubChem CID 5284595
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Allylnormorphine
- Lethidrone
- Nalorphine Hydrobromide
- Nalorphine Hydrochloride
- Nalorphine, (14 alpha)-Isomer
- Nalorphine, L-tartrate (1:1)
- Hydrobromide, Nalorphine
- Hydrochloride, Nalorphine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Nalorphine. Medical Subject Headings (MeSH). 2026. Unique ID D009269. http://id.nlm.nih.gov/mesh/2026/D009269
- Nalorphine. In: Wikipedia. https://en.wikipedia.org/wiki/Nalorphine
- Nalorphine. In: Wikidata. https://www.wikidata.org/wiki/Q2622916
- Nalorphine. In: PubChem Compound. CID 5284595. https://pubchem.ncbi.nlm.nih.gov/compound/5284595