Chemicals and Drugs

Nafoxidine

An estrogen antagonist that has been used in the treatment of breast cancer.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An estrogen antagonist that has been used in the treatment of breast cancer.

Chemical Identity

Chemical Information

Molecular Formula
C29H31NO2
Molecular Weight
425.6 g/mol
CAS Registry No.
1845-11-0
IUPAC Name
1-[2-[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine
InChIKey
JEYWNNAZDLFBFF-UHFFFAOYSA-N
SMILES
COC1=CC2=C(C=C1)C(=C(CC2)C3=CC=CC=C3)C4=CC=C(C=C4)OCCN5CCCC5
MeSH Unique ID
D009256
Source
PubChem CID 4416

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Nafoxidine Hydrochloride
  • U-11,100A
  • U-11000A
  • Hydrochloride, Nafoxidine
  • U 11,100A
  • U 11000A
  • U11,100A
  • U11000A

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(73); was see under PYRROLIDINES 1973-90

MeSH Hierarchy

Tree Number

  1. D03w.383.773.589w

AMA Style

References

  1. National Library of Medicine. Nafoxidine. Medical Subject Headings (MeSH). 2026. Unique ID D009256. http://id.nlm.nih.gov/mesh/2026/D009256
  2. Nafoxidine. In: Wikipedia. https://en.wikipedia.org/wiki/Nafoxidine
  3. Nafoxidine. In: Wikidata. https://www.wikidata.org/wiki/Q6958201
  4. Nafoxidine. In: PubChem Compound. CID 4416. https://pubchem.ncbi.nlm.nih.gov/compound/4416