Chemicals and Drugs

Nadolol

A non-selective beta-adrenergic antagonist with a long half-life, used in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension. Nadolol is also used for MIGRAINE DISORDERS and for tremor.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-selective beta-adrenergic antagonist with a long half-life, used in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension. Nadolol is also used for MIGRAINE DISORDERS and for tremor.

Chemical Identity

Chemical Information

Molecular Formula
C17H27NO4
Molecular Weight
309.4 g/mol
CAS Registry No.
42200-33-9
IUPAC Name
(2R,3S)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
InChIKey
VWPOSFSPZNDTMJ-UCWKZMIHSA-N
SMILES
CC(C)(C)NCC(COC1=CC=CC2=C1C[C@@H]([C@@H](C2)O)O)O
MeSH Unique ID
D009248
Source
PubChem CID 39147

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Corgard
  • SQ-11725
  • Solgol
  • SQ 11725
  • SQ11725

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Adrenergic Beta Receptor Blockaders (1969-1986)
  • Propanolamines (1974-1986)

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.624w.698.601w
  2. D02w.033w.755.624w.698.601w
  3. D02w.092w.063w.624w.698.601w

AMA Style

References

  1. National Library of Medicine. Nadolol. Medical Subject Headings (MeSH). 2026. Unique ID D009248. http://id.nlm.nih.gov/mesh/2026/D009248
  2. Nadolol. In: Wikipedia. https://en.wikipedia.org/wiki/Nadolol
  3. Nadolol. In: Wikidata. https://www.wikidata.org/wiki/Q424952
  4. Nadolol. In: PubChem Compound. CID 39147. https://pubchem.ncbi.nlm.nih.gov/compound/39147