Chemicals and Drugs

Nabumetone

A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.

Chemical Identity

Chemical Information

Molecular Formula
C15H16O2
Molecular Weight
228.29 g/mol
CAS Registry No.
42924-53-8
IUPAC Name
4-(6-methoxynaphthalen-2-yl)butan-2-one
InChIKey
BLXXJMDCKKHMKV-UHFFFAOYSA-N
SMILES
CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC
MeSH Unique ID
D000077430
Source
PubChem CID 4409

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • 4-(6-Methoxy-2-naphthyl)-2-butanone
  • Nabumeton
  • Apo-Nabumetone
  • Arthraxan
  • BRL 14777
  • Gen-Nabumetone
  • Listran
  • Mebutan
  • Nabucox
  • Relafen
  • Relif
  • Relifex
  • Rhoxal-nabumetone
  • ApoNabumetone
  • Rhoxal nabumetone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1982)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Nabumetone. Medical Subject Headings (MeSH). 2026. Unique ID D000077430. http://id.nlm.nih.gov/mesh/2026/D000077430
  2. Nabumetone. In: Wikipedia. https://en.wikipedia.org/wiki/Nabumetone
  3. Nabumetone. In: Wikidata. https://www.wikidata.org/wiki/Q425207
  4. Nabumetone. In: PubChem Compound. CID 4409. https://pubchem.ncbi.nlm.nih.gov/compound/4409