Structured Summary
Abstract
An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
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Classification
Broader headings
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Synonyms
11 entry terms
- I Kappa B-alpha Protein
- IKappaB-alpha
- IKappaBalpha
- Major Histocompatibility Complex Enhancer-Binding Protein MAD3
- p40 Protein (IKappaB-alpha)
- I Kappa B alpha Protein
- IKappaB alpha
- Inhibitor alpha, NF-KappaB
- Major Histocompatibility Complex Enhancer Binding Protein MAD3
- NF KappaB Inhibitor alpha
- alpha, NF-KappaB Inhibitor
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1991)
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Tree Numbers
AMA Style
References
- National Library of Medicine. NF-KappaB Inhibitor alpha. Medical Subject Headings (MeSH). 2026. Unique ID D000072000. http://id.nlm.nih.gov/mesh/2026/D000072000
- NF-KappaB Inhibitor alpha. In: Wikidata. https://www.wikidata.org/wiki/Q6103521