Structured Summary
Abstract
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.
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Classification
Broader headings
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MeSH Record
Synonyms
11 entry terms
- Type 5 Voltage-Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 5
- NAV1.5 Voltage Gated Sodium Channel
- Type 5 Voltage Gated Sodium Channel
- Voltage Gated Sodium Channel Type 5
- SCN5A Sodium Channel alpha Subunit
- Sodium Channel Protein Type 5 Subunit alpha
- Sodium Channel, Voltage-Gated, Type V, alpha Subunit
- Voltage-Gated Na+ Channel Na(v)1.5a
- Voltage-Gated Sodium Channel Type 5 Subunit alpha
- Voltage Gated Sodium Channel Type 5 Subunit alpha
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2013
MeSH Record
Previous Indexing
- Sodium Channels (2002-2012)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. NAV1.5 Voltage-Gated Sodium Channel. Medical Subject Headings (MeSH). 2026. Unique ID D062554. http://id.nlm.nih.gov/mesh/2026/D062554
- NAV1.5 Voltage-Gated Sodium Channel. In: Wikidata. https://www.wikidata.org/wiki/Q24767937