Chemicals and Drugs

N-Terminal Acetyltransferase A

An N-terminal acetyltransferase subtype that consists of the Naa10p catalytic subunit and the Naa15p auxiliary subunit. The structure of this enzyme is conserved between lower and higher eukaryotes. It has specificity for N-terminal SERINE; ALANINE; THREONINE; GLYCINE; VALINE; and CYSTINE residues and acts on nascent peptide chains after the removal of the initiator METHIONINE by METHIONYL AMINOPEPTIDASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An N-terminal acetyltransferase subtype that consists of the Naa10p catalytic subunit and the Naa15p auxiliary subunit. The structure of this enzyme is conserved between lower and higher eukaryotes. It has specificity for N-terminal SERINE; ALANINE; THREONINE; GLYCINE; VALINE; and CYSTINE residues and acts on nascent peptide chains after the removal of the initiator METHIONINE by METHIONYL AMINOPEPTIDASES.

MeSH Record

Classification

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MeSH Record

Synonyms

6 entry terms
  • N-Terminal Acetyltransferase Type A
  • NatA N-Terminal Acetyltransferase
  • N Terminal Acetyltransferase A
  • N Terminal Acetyltransferase Type A
  • N-Terminal Acetyltransferase, NatA
  • NatA N Terminal Acetyltransferase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Record

Previous Indexing

  • Acetyltransferases (1974-2012)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. N-Terminal Acetyltransferase A. Medical Subject Headings (MeSH). 2026. Unique ID D063209. http://id.nlm.nih.gov/mesh/2026/D063209
  2. N-Terminal Acetyltransferase A. In: Wikidata. https://www.wikidata.org/wiki/Q21112508