Chemicals and Drugs

N-Formylmethionine

Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

Chemical Identity

Chemical Information

Molecular Formula
C6H11NO3S
Molecular Weight
177.22 g/mol
CAS Registry No.
4309-82-4
IUPAC Name
2-formamido-4-methylsulfanylbutanoic acid
InChIKey
PYUSHNKNPOHWEZ-UHFFFAOYSA-N
SMILES
CSCCC(C(=O)O)NC=O
MeSH Unique ID
D009239
Source
PubChem CID 911

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • N Formylmethionine
  • Formylmethionine, N

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under METHIONINE 1975-90

MeSH Record

Previous Indexing

  • Formic Acids (1974)
  • Methionine (1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. N-Formylmethionine. Medical Subject Headings (MeSH). 2026. Unique ID D009239. http://id.nlm.nih.gov/mesh/2026/D009239
  2. N-Formylmethionine. In: Wikipedia. https://en.wikipedia.org/wiki/N-Formylmethionine
  3. N-Formylmethionine. In: Wikidata. https://www.wikidata.org/wiki/Q307455
  4. N-Formylmethionine. In: PubChem Compound. CID 911. https://pubchem.ncbi.nlm.nih.gov/compound/911