Chemicals and Drugs

N-Acetylmuramoyl-L-alanine Amidase

An autolytic enzyme bound to the surface of bacterial cell walls. It catalyzes the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan. EC 3.5.1.28.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autolytic enzyme bound to the surface of bacterial cell walls. It catalyzes the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan. EC 3.5.1.28.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

15 entry terms
  • LE-Enzyme
  • Mucopeptide Amidohydrolase
  • Murein Hydrolase
  • Peptidoglycan Hydrolase
  • Amidase, N-Acetylmuramoyl-L-alanine
  • Amidohydrolase, Mucopeptide
  • Hydrolase, Murein
  • Hydrolase, Peptidoglycan
  • LE Enzyme
  • N Acetylmuramoyl L alanine Amidase
  • Autolysin
  • T7 Endolysin
  • T7 Lysozyme
  • Endolysin, T7
  • Lysozyme, T7

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(79); was see under AMIDOHYDROLASES 1979-90

MeSH Record

Previous Indexing

  • Alanine (1966-1978)
  • Amidohydrolases (1966-1978)
  • Muramic Acids (1973-1978)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. N-Acetylmuramoyl-L-alanine Amidase. Medical Subject Headings (MeSH). 2026. Unique ID D009238. http://id.nlm.nih.gov/mesh/2026/D009238
  2. N-Acetylmuramoyl-L-alanine Amidase. In: Wikipedia. https://en.wikipedia.org/wiki/N-acetylmuramoyl-L-alanine_amidase
  3. N-Acetylmuramoyl-L-alanine Amidase. In: Wikidata. https://www.wikidata.org/wiki/Q6951440