Structured Summary
Abstract
An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
8 entry terms
- Myosin Kinase
- Myosin LCK
- Myosin Regulatory Light-Chain Kinase
- Kinase, Myosin
- Kinase, Myosin-Light-Chain
- LCK, Myosin
- Myosin Light Chain Kinase
- Myosin Regulatory Light Chain Kinase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
87
MeSH Record
Previous Indexing
- Phosphotransferases, ATP (1966-1972)
- Protein Kinases (1973-1986)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Myosin-Light-Chain Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D009219. http://id.nlm.nih.gov/mesh/2026/D009219
- Myosin-Light-Chain Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q21114653