Structured Summary
Abstract
A secreted glycoprotein that controls activation of signaling pathways in adjacent cells (PARACRINE COMMUNICATION) for processes that include CELL ADHESION; CELL MIGRATION; and organization of the CYTOSKELETON. It is primarily expressed in the RETINA and variants in the myocillin gene cause GLAUCOMA 1, OPEN ANGLE, A.
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Classification
Broader headings
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MeSH Record
Synonyms
4 entry terms
- GLC1A Protein
- MYOC Protein
- TIGR Protein
- Trabecular Meshwork-induced Glucocorticoid Response Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2026 (1997); use TRABECULAR MESHWORK-INDUCED GLUCOCORTICOID RESPONSE PROTEIN (NM) 1997-2025
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Myocilin. Medical Subject Headings (MeSH). 2026. Unique ID D000099179. http://id.nlm.nih.gov/mesh/2026/D000099179
- Myocilin. In: Wikidata. https://www.wikidata.org/wiki/Q24785331