Structured Summary
Abstract
A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.
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Synonyms
7 entry terms
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
- Myeloid Cell Factor-1
- Myeloid Cell Leukemia Sequence 1
- Cell Factor-1, Myeloid
- Factor-1, Myeloid Cell
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1
- Myeloid Cell Factor 1
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2014
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References
- National Library of Medicine. Myeloid Cell Leukemia Sequence 1 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D064549. http://id.nlm.nih.gov/mesh/2026/D064549
- Myeloid Cell Leukemia Sequence 1 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21112678