Diseases

Myasthenia Gravis

A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

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Synonyms

14 entry terms
  • Anti-MuSK Myasthenia Gravis
  • MuSK MG
  • MuSK Myasthenia Gravis
  • Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis
  • Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis
  • Myasthenia Gravis, Generalized
  • Myasthenia Gravis, Ocular
  • Anti MuSK Myasthenia Gravis
  • Generalized Myasthenia Gravis
  • Muscle Specific Receptor Tyrosine Kinase Myasthenia Gravis
  • Muscle Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis
  • Myasthenia Gravis, Anti-MuSK
  • Myasthenia Gravis, MuSK
  • Ocular Myasthenia Gravis

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Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

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Indexing Annotation

"myasthenia" unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congenital: consider MYASTHENIC SYNDROMES, CONGENITAL or specifics

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Tree Numbers

  1. C04w.588.614w.550.500w
  2. C04w.730w.856.490w
  3. C10w.114.656w
  4. C10w.574w.781.588w
  5. C10w.668w.758w.725w
  6. C20w.111w.258.500w

MeSH Record

NLM Classification

WE 555

AMA Style

References

  1. National Library of Medicine. Myasthenia Gravis. Medical Subject Headings (MeSH). 2026. Unique ID D009157. http://id.nlm.nih.gov/mesh/2026/D009157
  2. Myasthenia Gravis. In: Wikipedia. https://en.wikipedia.org/wiki/Myasthenia_gravis
  3. Myasthenia Gravis. In: Wikidata. https://www.wikidata.org/wiki/Q8285