Structured Summary
Abstract
Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti).
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Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- Monoclonal Antibody OKT3
- OKT3
- Muromonab CD3
- Orthoclone OKT3
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, drug therapy, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not coordinate with ANTIBODY FORMATION for biosyn
MeSH Record
History Note
92; MONOCLONAL ANTIBODY OKT3 was MONOCLONAL ANTIBODY OKT3, ORTHOCLONE (NM) 1987-91
MeSH Record
Previous Indexing
- Antibodies, Monoclonal (1981-1991)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Muromonab-CD3. Medical Subject Headings (MeSH). 2026. Unique ID D016853. http://id.nlm.nih.gov/mesh/2026/D016853
- Muromonab-CD3. In: Wikipedia. https://en.wikipedia.org/wiki/Muromonab-CD3
- Muromonab-CD3. In: Wikidata. https://www.wikidata.org/wiki/Q416494