Structured Summary
Abstract
A topically used antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing.
Chemical Identity
Chemical Information
- Molecular Formula
- C26H44O9
- Molecular Weight
- 500.6 g/mol
- CAS Registry No.
- 12650-69-0
- IUPAC Name
- 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
- InChIKey
- MINDHVHHQZYEEK-HBBNESRFSA-N
- SMILES
- C[C@H]([C@H]1[C@@H](O1)C[C@H]2CO[C@H]([C@@H]([C@@H]2O)O)C/C(=C/C(=O)OCCCCCCCCC(=O)O)/C)[C@H](C)O
- MeSH Unique ID
- D016712
- Source
- PubChem CID 446596
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
14 entry terms
- Pseudomonic Acid A
- BRL-4910A
- Bactroban
- Mupirocin Calcium
- Mupirocin, 14C-Labeled
- Mupirocin, Calcium Salt (2:1)
- Mupirocin, Calcium Salt (2:1), Dihydrate
- Mupirocin, Lithium Salt
- Mupirocin, Sodium Salt
- Pseudomonic Acid
- 14C-Labeled Mupirocin
- BRL 4910A
- BRL4910A
- Mupirocin, 14C Labeled
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1992; was PSEUDOMONIC ACID (NM) 1977-91
MeSH Record
Previous Indexing
- Antibiotics (1966-1991)
- Fatty Acids (1966-1991)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Mupirocin. Medical Subject Headings (MeSH). 2026. Unique ID D016712. http://id.nlm.nih.gov/mesh/2026/D016712
- Mupirocin. In: Wikipedia. https://en.wikipedia.org/wiki/Mupirocin
- Mupirocin. In: Wikidata. https://www.wikidata.org/wiki/Q413578
- Mupirocin. In: PubChem Compound. CID 446596. https://pubchem.ncbi.nlm.nih.gov/compound/446596