Chemicals and Drugs

Morphine

The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.

National Library of MedicineMedical Subject Headings2026
Molecular structure visualization for Morphine
PubChem CID 5288826Open interactive model

Structured Summary

Abstract

The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.

Chemical Identity

Chemical Information

Molecular Formula
C17H19NO3
Molecular Weight
285.34 g/mol
CAS Registry No.
57-27-2
IUPAC Name
(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
InChIKey
BQJCRHHNABKAKU-KBQPJGBKSA-N
SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
MeSH Unique ID
D009020
Source
PubChem CID 5288826

Interactive Figure

3D Structure

Drag to rotate; scroll or pinch to zoom. Ball-and-stick model from the PubChem 3D conformer.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

17 entry terms
  • Morphia
  • Duramorph
  • MS Contin
  • Morphine Chloride
  • Morphine Sulfate
  • Morphine Sulfate (2:1), Anhydrous
  • Morphine Sulfate (2:1), Pentahydrate
  • Oramorph SR
  • SDZ 202-250
  • SDZ202-250
  • Chloride, Morphine
  • Contin, MS
  • SDZ 202 250
  • SDZ 202250
  • SDZ202 250
  • SDZ202250
  • Sulfate, Morphine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/analogs = MORPHINE DERIVATIVES

MeSH Record

History Note

MORPHINE SULFATE was (NM) 1980-96

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.577.249.562.571w
  2. D03w.605.497.607.587w
  3. D03w.633.400.686.607.587w
  4. D04w.615w.723w.795.576.571w

MeSH Record

NLM Classification

QV 92

AMA Style

References

  1. National Library of Medicine. Morphine. Medical Subject Headings (MeSH). 2026. Unique ID D009020. http://id.nlm.nih.gov/mesh/2026/D009020
  2. Morphine. In: Wikipedia. https://en.wikipedia.org/wiki/Morphine
  3. Morphine. In: Wikidata. https://www.wikidata.org/wiki/Q81225
  4. Morphine. In: PubChem Compound. CID 5288826. https://pubchem.ncbi.nlm.nih.gov/compound/5288826