Structured Summary
Abstract
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
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Synonyms
11 entry terms
- Leukocyte Culture Test, Mixed
- Lymphocyte Culture Test, Mixed
- Mixed Leukocyte Culture Test
- Mixed Leukocyte Reaction
- Mixed Lymphocyte Reaction
- Leukocyte Reaction, Mixed
- Leukocyte Reactions, Mixed
- Lymphocyte Reaction, Mixed
- Lymphocyte Reactions, Mixed
- Mixed Leukocyte Reactions
- Mixed Lymphocyte Reactions
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Aspects Covered
12 allowable subheadings
Indexed with the subheadings adverse effects, classification, economics, ethics, history, instrumentation, methods, mortality, standards, statistics & numerical data, trends, veterinary.
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NIM
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History Note
93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
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Previous Indexing
- Histocompatibility Testing (1968-1972)
- Leukocytes (1966-1972)
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AMA Style
References
- National Library of Medicine. Mixed Lymphocyte Culture Test. Medical Subject Headings (MeSH). 2026. Unique ID D007959. http://id.nlm.nih.gov/mesh/2026/D007959
- Mixed Lymphocyte Culture Test. In: Wikidata. https://www.wikidata.org/wiki/Q73502423