Chemicals and Drugs

Mitomycins

A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.

MeSH Record

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

MITOMYCIN is also available

MeSH Record

History Note

82; was MITOMYCIN 1963-81

MeSH Hierarchy

Tree Numbers

  1. D02w.806w.400w.249w
  2. D03w.383.097.500w
  3. D03w.633.100.473.412w.249w

MeSH Record

NLM Classification

QV 269

AMA Style

References

  1. National Library of Medicine. Mitomycins. Medical Subject Headings (MeSH). 2026. Unique ID D008937. http://id.nlm.nih.gov/mesh/2026/D008937
  2. Mitomycins. In: Wikipedia. https://en.wikipedia.org/wiki/Mitomycins
  3. Mitomycins. In: Wikidata. https://www.wikidata.org/wiki/Q417625