Chemicals and Drugs

Mitoguazone

Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.

Chemical Identity

Chemical Information

Molecular Formula
C5H12N8
Molecular Weight
184.20 g/mol
CAS Registry No.
459-86-9
IUPAC Name
2-[(E)-[(1E)-1-(diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine
InChIKey
MXWHMTNPTTVWDM-NXOFHUPFSA-N
SMILES
C/C(=N\N=C(N)N)/C=N/N=C(N)N
MeSH Unique ID
D008935
Source
PubChem CID 5351154

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • MGBG
  • Methylglyoxal Bis(guanylhydrazone)
  • Methyl-gag
  • NSC-32946
  • Methyl gag
  • Methylgag
  • NSC 32946
  • NSC32946

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

86(75); was see under GUANIDINES 1975-85

MeSH Record

Previous Indexing

  • Amidines (1973-1974)
  • Glyoxal (1973-1974)
  • Hydrazones (1973-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Mitoguazone. Medical Subject Headings (MeSH). 2026. Unique ID D008935. http://id.nlm.nih.gov/mesh/2026/D008935
  2. Mitoguazone. In: Wikipedia. https://en.wikipedia.org/wiki/Mitoguazone
  3. Mitoguazone. In: Wikidata. https://www.wikidata.org/wiki/Q6881893
  4. Mitoguazone. In: PubChem Compound. CID 5351154. https://pubchem.ncbi.nlm.nih.gov/compound/5351154