Chemicals and Drugs

Mitochondrial Processing Peptidase

A hetero-dimeric protein consisting of two subunits, alpha and beta, which are referred to as PMPCA and PMPCB in humans. It plays an essential role in removing the N-terminal targeting peptidase from precursor proteins imported into the mitochondria.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A hetero-dimeric protein consisting of two subunits, alpha and beta, which are referred to as PMPCA and PMPCB in humans. It plays an essential role in removing the N-terminal targeting peptidase from precursor proteins imported into the mitochondria.

MeSH Record

Classification

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MeSH Record

Synonyms

12 entry terms
  • Matrix Processing Peptidase
  • Mitochondrial Processing Protease
  • Peptidase, Matrix Processing
  • Peptidase, Mitochondrial Processing
  • Processing Peptidase, Matrix
  • Processing Peptidase, Mitochondrial
  • Processing Protease, Mitochondrial
  • Protease, Mitochondrial Processing
  • alpha-MPP
  • beta-MPP
  • alpha MPP
  • beta MPP

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2024 (1990)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Mitochondrial Processing Peptidase. Medical Subject Headings (MeSH). 2026. Unique ID D000096122. http://id.nlm.nih.gov/mesh/2026/D000096122
  2. Mitochondrial Processing Peptidase. In: Wikipedia. https://en.wikipedia.org/wiki/Mitochondrial_processing_peptidase
  3. Mitochondrial Processing Peptidase. In: Wikidata. https://www.wikidata.org/wiki/Q13100026