Structured Summary
Abstract
A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.
Chemical Identity
Chemical Information
- Molecular Formula
- C7H11N3O4
- Molecular Weight
- 201.18 g/mol
- CAS Registry No.
- 13551-87-6
- IUPAC Name
- 1-methoxy-3-(2-nitroimidazol-1-yl)propan-2-ol
- InChIKey
- OBBCSXFCDPPXOL-UHFFFAOYSA-N
- SMILES
- COCC(CN1C=CN=C1[N+](=O)[O-])O
- MeSH Unique ID
- D008920
- Source
- PubChem CID 26105
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- alpha-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol
- Ro 07-0582
- Ro 7-0582
- Ro 07 0582
- Ro 070582
- Ro 7 0582
- Ro 70582
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
86(79); was see under NITROIMIDAZOLES 1979-85
MeSH Record
Previous Indexing
- Imidazoles (1966-1973)
- Nitroimidazoles (1974-1978)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Misonidazole. Medical Subject Headings (MeSH). 2026. Unique ID D008920. http://id.nlm.nih.gov/mesh/2026/D008920
- Misonidazole. In: Wikipedia. https://en.wikipedia.org/wiki/Misonidazole
- Misonidazole. In: Wikidata. https://www.wikidata.org/wiki/Q6875874
- Misonidazole. In: PubChem Compound. CID 26105. https://pubchem.ncbi.nlm.nih.gov/compound/26105