Chemicals and Drugs

Midodrine

An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.

Chemical Identity

Chemical Information

Molecular Formula
C12H18N2O4
Molecular Weight
254.28 g/mol
CAS Registry No.
42794-76-3
IUPAC Name
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
InChIKey
PTKSEFOSCHHMPD-UHFFFAOYSA-N
SMILES
COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O
MeSH Unique ID
D008879
Source
PubChem CID 4195

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Midodrin
  • Amatine
  • Gutron
  • Midodrine Hydrochloride
  • Midodrine Monohydrochloride
  • Midon
  • ProAmatine
  • ST-1085
  • Monohydrochloride, Midodrine
  • ST 1085
  • ST1085

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

96; was MIDODRIN 1975-95 (see under ETHANOLAMINES 1975-90)

MeSH Record

Previous Indexing

  • Ethanolamines (1973-1974)
  • Glycine (1973-1974)
  • Hydroquinones (1973-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Midodrine. Medical Subject Headings (MeSH). 2026. Unique ID D008879. http://id.nlm.nih.gov/mesh/2026/D008879
  2. Midodrine. In: Wikipedia. https://en.wikipedia.org/wiki/Midodrine
  3. Midodrine. In: Wikidata. https://www.wikidata.org/wiki/Q415051
  4. Midodrine. In: PubChem Compound. CID 4195. https://pubchem.ncbi.nlm.nih.gov/compound/4195