Chemicals and Drugs

Mianserin

A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.

Chemical Identity

Chemical Information

Molecular Formula
C18H20N2
Molecular Weight
264.4 g/mol
CAS Registry No.
24219-97-4
IUPAC Name
5-methyl-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaene
InChIKey
UEQUQVLFIPOEMF-UHFFFAOYSA-N
SMILES
CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42
MeSH Unique ID
D008803
Source
PubChem CID 4184

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Lerivon
  • Mianserin Hydrochloride
  • Mianserin Monohydrochloride
  • Org GB 94
  • Tolvon
  • Hydrochloride, Mianserin
  • Monohydrochloride, Mianserin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87(75); was see under DIBENZAZEPINES 1975-86

MeSH Record

Previous Indexing

  • Dibenzazepines (1972-1974)
  • Pyrazines (1972-1974)

MeSH Hierarchy

Tree Number

  1. D03w.633.300.240.550w

AMA Style

References

  1. National Library of Medicine. Mianserin. Medical Subject Headings (MeSH). 2026. Unique ID D008803. http://id.nlm.nih.gov/mesh/2026/D008803
  2. Mianserin. In: Wikipedia. https://en.wikipedia.org/wiki/Mianserin
  3. Mianserin. In: Wikidata. https://www.wikidata.org/wiki/Q416701
  4. Mianserin. In: PubChem Compound. CID 4184. https://pubchem.ncbi.nlm.nih.gov/compound/4184