Chemicals and Drugs

Mexiletine

Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.

Chemical Identity

Chemical Information

Molecular Formula
C11H17NO
Molecular Weight
179.26 g/mol
CAS Registry No.
31828-71-4
IUPAC Name
1-(2,6-dimethylphenoxy)propan-2-amine
InChIKey
VLPIATFUUWWMKC-UHFFFAOYSA-N
SMILES
CC1=C(C(=CC=C1)C)OCC(C)N
MeSH Unique ID
D008801
Source
PubChem CID 4178

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • KO-1173
  • KO1173
  • KOE-1173
  • Mexiletene
  • Mexiletine Hydrochloride
  • Mexitil
  • Mexitil PL
  • Mexityl
  • Novo-Mexiletine
  • KO 1173
  • KOE 1173
  • KOE1173
  • Novo Mexiletine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87(75); was see under PROPYLAMINES 1975-86

MeSH Record

Previous Indexing

  • Phenyl Ethers (1974)
  • Propylamines (1972-1974)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 152

AMA Style

References

  1. National Library of Medicine. Mexiletine. Medical Subject Headings (MeSH). 2026. Unique ID D008801. http://id.nlm.nih.gov/mesh/2026/D008801
  2. Mexiletine. In: Wikipedia. https://en.wikipedia.org/wiki/Mexiletine
  3. Mexiletine. In: Wikidata. https://www.wikidata.org/wiki/Q420377
  4. Mexiletine. In: PubChem Compound. CID 4178. https://pubchem.ncbi.nlm.nih.gov/compound/4178