Chemicals and Drugs

Methylthiouracil

A thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism.

Chemical Identity

Chemical Information

Molecular Formula
C5H6N2OS
Molecular Weight
142.18 g/mol
CAS Registry No.
56-04-2
IUPAC Name
6-methyl-2-sulfanylidene-1H-pyrimidin-4-one
InChIKey
HWGBHCRJGXAGEU-UHFFFAOYSA-N
SMILES
CC1=CC(=O)NC(=S)N1
MeSH Unique ID
D008779
Source
PubChem CID 667493

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • 4-Methyl-2-thiouracil
  • Alkiron
  • Metacil
  • Thimecil

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D03w.383.742.698.875w.842w.455w

AMA Style

References

  1. National Library of Medicine. Methylthiouracil. Medical Subject Headings (MeSH). 2026. Unique ID D008779. http://id.nlm.nih.gov/mesh/2026/D008779
  2. Methylthiouracil. In: Wikipedia. https://en.wikipedia.org/wiki/Methylthiouracil
  3. Methylthiouracil. In: Wikidata. https://www.wikidata.org/wiki/Q6824062
  4. Methylthiouracil. In: PubChem Compound. CID 667493. https://pubchem.ncbi.nlm.nih.gov/compound/667493