Chemicals and Drugs

Methylprednisolone Hemisuccinate

A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.

Chemical Identity

Chemical Information

Molecular Formula
C26H34O8
Molecular Weight
474.5 g/mol
CAS Registry No.
2921-57-5
IUPAC Name
4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
InChIKey
IMBXEJJVJRTNOW-XYMSELFBSA-N
SMILES
C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)O)O
MeSH Unique ID
D008776
Source
PubChem CID 16923

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Methylprednisolone Succinate
  • Hemisuccinate, Methylprednisolone
  • Succinate, Methylprednisolone
  • 6 alpha-Methylprednisolone Sodium Hemisuccinate
  • A-MethaPred
  • Methylprednisolone Hemisuccinate Monosodium Salt
  • Methylprednisolone Sodium Hemisuccinate
  • Methylprednisolone Sodium Succinate
  • Solu-Medrol
  • Solumedrol
  • Urbason-Soluble
  • Sodium Hemisuccinate, Methylprednisolone
  • Sodium Succinate, Methylprednisolone
  • UrbasonSoluble

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(80); was METHYLPREDNISOLONE SUCCINATE see under METHYLPREDNISOLONE/analogs & derivatives 1980-90

MeSH Record

Previous Indexing

  • Methylprednisolone (1966-1974)/analogs & derivatives (1975-1979)
  • Succinates (1966-1979)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.745.432w.769.795w.539w.500

MeSH Record

NLM Classification

WK 755

AMA Style

References

  1. National Library of Medicine. Methylprednisolone Hemisuccinate. Medical Subject Headings (MeSH). 2026. Unique ID D008776. http://id.nlm.nih.gov/mesh/2026/D008776
  2. Methylprednisolone Hemisuccinate. In: Wikidata. https://www.wikidata.org/wiki/Q27262132
  3. Methylprednisolone Hemisuccinate. In: PubChem Compound. CID 16923. https://pubchem.ncbi.nlm.nih.gov/compound/16923