Chemicals and Drugs

Methylmalonyl-CoA Decarboxylase

A carboxy-lyase that catalyzes the DECARBOXYLATION of (S)-2-Methyl-3-oxopropanoyl-CoA to propanoyl-CoA. In microorganisms the reaction can be coupled to the vectorial transport of SODIUM ions across the cytoplasmic membrane.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A carboxy-lyase that catalyzes the DECARBOXYLATION of (S)-2-Methyl-3-oxopropanoyl-CoA to propanoyl-CoA. In microorganisms the reaction can be coupled to the vectorial transport of SODIUM ions across the cytoplasmic membrane.

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Synonyms

6 entry terms
  • (S)-methylmalonyl-CoA Decarboxylase (Sodium-Transporting)
  • Methylmalonyl-Coenzyme A Decarboxylase
  • Decarboxylase, Methylmalonyl-CoA
  • Decarboxylase, Methylmalonyl-Coenzyme A
  • Methylmalonyl CoA Decarboxylase
  • Methylmalonyl Coenzyme A Decarboxylase

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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History Note

2004; use METHYLMALONYL-COA DECARBOXYLASE (NM) 1980-2003

MeSH Record

Previous Indexing

  • Carboxy-Lyases (1983-2003)
  • Propionates (1984-2003)

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AMA Style

References

  1. National Library of Medicine. Methylmalonyl-CoA Decarboxylase. Medical Subject Headings (MeSH). 2026. Unique ID D043586. http://id.nlm.nih.gov/mesh/2026/D043586
  2. Methylmalonyl-CoA Decarboxylase. In: Wikipedia. https://en.wikipedia.org/wiki/Methylmalonyl-CoA_decarboxylase
  3. Methylmalonyl-CoA Decarboxylase. In: Wikidata. https://www.wikidata.org/wiki/Q13362740