Chemicals and Drugs

Methylenetetrahydrofolate Reductase (NADPH2)

A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.

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Classification

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MeSH Record

Synonyms

6 entry terms
  • 5,10-Methylenetetrahydrofolate Reductase (NADPH)
  • Methylene Tetrahydrofolate Reductase
  • Methylene-THF Reductase (NADPH)
  • Methylenetetrahydrofolate Reductase
  • Methylenetetrahydrofolate Reductase (NADPH)
  • Tetrahydrofolate Reductase, Methylene

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2) (NM) 1986-2003

MeSH Record

Previous Indexing

  • Amine Oxidoreductases (1986-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Methylenetetrahydrofolate Reductase (NADPH2). Medical Subject Headings (MeSH). 2026. Unique ID D042965. http://id.nlm.nih.gov/mesh/2026/D042965
  2. Methylenetetrahydrofolate Reductase (NADPH2). In: Wikipedia. https://en.wikipedia.org/wiki/Methylenetetrahydrofolate_reductase
  3. Methylenetetrahydrofolate Reductase (NADPH2). In: Wikidata. https://www.wikidata.org/wiki/Q424709