Chemicals and Drugs

Methoxsalen

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.

Chemical Identity

Chemical Information

Molecular Formula
C12H8O4
Molecular Weight
216.19 g/mol
CAS Registry No.
298-81-7
IUPAC Name
9-methoxyfuro[3,2-g]chromen-7-one
InChIKey
QXKHYNVANLEOEG-UHFFFAOYSA-N
SMILES
COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
MeSH Unique ID
D008730
Source
PubChem CID 4114

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

21 entry terms
  • 8-Methoxypsoralen
  • Ammoidin
  • Xanthotoxin
  • 8 Methoxypsoralen
  • 8-MOP
  • Deltasoralen
  • Dermox
  • Geroxalen
  • Meladinina
  • Meladinine
  • Meloxine
  • Methoxa-Dome
  • Méladinine
  • Oxsoralen
  • Oxsoralen-Ultra
  • Puvalen
  • Ultramop
  • 8 MOP
  • 8MOP
  • Methoxa Dome
  • Oxsoralen Ultra

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not index here for use in PUVA THERAPY unless particularly discussed

MeSH Hierarchy

Tree Numbers

  1. D03w.383.663.283.446w.794w.500w
  2. D03w.633.100.150.446w.794w.500w
  3. D03w.633.300.770w.500w

AMA Style

References

  1. National Library of Medicine. Methoxsalen. Medical Subject Headings (MeSH). 2026. Unique ID D008730. http://id.nlm.nih.gov/mesh/2026/D008730
  2. Methoxsalen. In: Wikipedia. https://en.wikipedia.org/wiki/Methoxsalen
  3. Methoxsalen. In: Wikidata. https://www.wikidata.org/wiki/Q408570
  4. Methoxsalen. In: PubChem Compound. CID 4114. https://pubchem.ncbi.nlm.nih.gov/compound/4114