Chemicals and Drugs

Methantheline

A quaternary ammonium compound that acts as an antimuscarinic agent. It has been used in the treatment of PEPTIC ULCER, in gastrointestinal disorders associated with smooth muscle spasm, and in the management of urinary incontinence, and may also be used for the treatment of HYPERHIDROSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A quaternary ammonium compound that acts as an antimuscarinic agent. It has been used in the treatment of PEPTIC ULCER, in gastrointestinal disorders associated with smooth muscle spasm, and in the management of urinary incontinence, and may also be used for the treatment of HYPERHIDROSIS.

Chemical Identity

Chemical Information

Molecular Formula
C21H26NO3+
Molecular Weight
340.4 g/mol
CAS Registry No.
5818-17-7
IUPAC Name
diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
InChIKey
GZHFODJQISUKAY-UHFFFAOYSA-N
SMILES
CC[N+](C)(CC)CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13
MeSH Unique ID
D000077771
Source
PubChem CID 4097

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Banthine
  • Methantheline Bromide
  • Vagantin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1963)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Methantheline. Medical Subject Headings (MeSH). 2026. Unique ID D000077771. http://id.nlm.nih.gov/mesh/2026/D000077771
  2. Methantheline. In: Wikipedia. https://en.wikipedia.org/wiki/Methantheline
  3. Methantheline. In: Wikidata. https://www.wikidata.org/wiki/Q6823610
  4. Methantheline. In: PubChem Compound. CID 4097. https://pubchem.ncbi.nlm.nih.gov/compound/4097