Structured Summary
Abstract
A broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.
Chemical Identity
Chemical Information
- Molecular Formula
- C22H22N2O8
- Molecular Weight
- 442.4 g/mol
- IUPAC Name
- (2Z,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
- InChIKey
- GLFJCEVWKWQSJP-ISFNZQQKSA-N
- SMILES
- CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=O)/C(=C(/N)\O)/C1=O)O)O)O
- MeSH Unique ID
- D008690
- Source
- PubChem CID 5281054
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Metacycline
- Methyleneoxytetracycline
- Lysocline
- Methacycline Monohydrochloride
- Physiomycine
- Rondomycin
- Monohydrochloride, Methacycline
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
68(65)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Methacycline. Medical Subject Headings (MeSH). 2026. Unique ID D008690. http://id.nlm.nih.gov/mesh/2026/D008690
- Methacycline. In: Wikipedia. https://en.wikipedia.org/wiki/Metacycline
- Methacycline. In: Wikidata. https://www.wikidata.org/wiki/Q2365033
- Methacycline. In: PubChem Compound. CID 5281054. https://pubchem.ncbi.nlm.nih.gov/compound/5281054