Chemicals and Drugs

Mesalamine

An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)

Chemical Identity

Chemical Information

Molecular Formula
C7H7NO3
Molecular Weight
153.14 g/mol
CAS Registry No.
89-57-6
IUPAC Name
5-amino-2-hydroxybenzoic acid
InChIKey
KBOPZPXVLCULAV-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1N)C(=O)O)O
MeSH Unique ID
D019804
Source
PubChem CID 4075

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

26 entry terms
  • 5-Aminosalicylic Acid
  • Mesalazine
  • m-Aminosalicylic Acid
  • meta-Aminosalicylic Acid
  • 5 Aminosalicylic Acid
  • m Aminosalicylic Acid
  • meta Aminosalicylic Acid
  • 5-Aminosalicylate
  • Asacol
  • Asacolon
  • Ascolitin
  • Canasa
  • Claversal
  • Fivasa
  • Lixacol
  • Mesalamine Hydrochloride
  • Mesalamine Monosodium Salt
  • Mesasal
  • Novo-5 ASA
  • Pentasa
  • Rowasa
  • Salofalk
  • 5 Aminosalicylate
  • Hydrochloride, Mesalamine
  • Monosodium Salt, Mesalamine
  • Novo 5 ASA

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

98; use MESALAMINE (NM) 1981-97

MeSH Record

Previous Indexing

  • Aminosalicylic Acids (1981-1997)

MeSH Hierarchy

Tree Numbers

  1. D02w.241w.223.100.050.300.500w
  2. D02w.241w.223.100.300.595w.100.540w
  3. D02w.241w.511w.390.595w.100.540w
  4. D02w.455w.426w.559w.389.127.020.452.750w
  5. D02w.455w.426w.559w.389.127.281.595w.100.540w
  6. D02w.455w.426w.559w.389.657w.410.595w.100.540w

AMA Style

References

  1. National Library of Medicine. Mesalamine. Medical Subject Headings (MeSH). 2026. Unique ID D019804. http://id.nlm.nih.gov/mesh/2026/D019804
  2. Mesalamine. In: Wikipedia. https://en.wikipedia.org/wiki/Mesalazine
  3. Mesalamine. In: Wikidata. https://www.wikidata.org/wiki/Q412479
  4. Mesalamine. In: PubChem Compound. CID 4075. https://pubchem.ncbi.nlm.nih.gov/compound/4075