Chemicals and Drugs

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

Chemical Identity

Chemical Information

Molecular Formula
C15H21NO2
Molecular Weight
247.33 g/mol
CAS Registry No.
57-42-1
IUPAC Name
ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
InChIKey
XADCESSVHJOZHK-UHFFFAOYSA-N
SMILES
CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
MeSH Unique ID
D008614
Source
PubChem CID 4058

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Isonipecain
  • Pethidine
  • Demerol
  • Dolantin
  • Dolargan
  • Dolcontral
  • Dolin
  • Dolosal
  • Dolsin
  • Lidol
  • Lydol
  • Meperidine Hydrochloride
  • Operidine EPJ-I
  • Operidine EPJ I

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

OPERIDINE was see MEPERIDINE 1978-91

MeSH Hierarchy

Tree Numbers

  1. D03w.066.399.450w
  2. D03w.383.621.349.450w

MeSH Record

NLM Classification

QV 89

AMA Style

References

  1. National Library of Medicine. Meperidine. Medical Subject Headings (MeSH). 2026. Unique ID D008614. http://id.nlm.nih.gov/mesh/2026/D008614
  2. Meperidine. In: Wikipedia. https://en.wikipedia.org/wiki/Pethidine
  3. Meperidine. In: Wikidata. https://www.wikidata.org/wiki/Q55434
  4. Meperidine. In: PubChem Compound. CID 4058. https://pubchem.ncbi.nlm.nih.gov/compound/4058